apixaban for lv thrombus | Lv thrombus treatment guidelines apixaban for lv thrombus Keywords: Apixaban, direct oral anticoagulants, DOACs, left ventricular thrombus, Rivaroxaban, thrombolysis. 1. BACKGROUND. Left ventricular thrombus (LVT) is a common complication following acute myocardial infarction (AMI) with potential for significant morbidity and mortality.
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Our results suggest that apixaban is non-inferior to warfarin for treatment of patients with LV thrombus after acute MI with a 20% non-inferiority margin. Apixaban versus warfarin in patients with left ventricular thrombus: a pilot prospective randomized outcome blinded study investigating size reduction or resolution of left . Our results suggest that apixaban is non-inferior to warfarin for treatment of patients with LV thrombus after acute MI with a 20% non-inferiority margin. Apixaban versus warfarin in patients with left ventricular thrombus: a pilot prospective randomized outcome blinded study investigating size reduction or resolution of left ventricular thrombus. J Clin Prev Cardiol 2020;9:150–4.
Results: Of the 514 patients with LV thrombi, 300 received warfarin, while 185 received DOAC therapy. DOAC use was most commonly apixaban (141/185, 76.2%) or rivaroxaban (46/185, 24.9%). Median follow-up was 351 days (interquartile range, [IQR], 51 .Keywords: Apixaban, direct oral anticoagulants, DOACs, left ventricular thrombus, Rivaroxaban, thrombolysis. 1. BACKGROUND. Left ventricular thrombus (LVT) is a common complication following acute myocardial infarction (AMI) with potential for significant morbidity and mortality.
Current guidelines recommend anticoagulation with a vitamin K antagonist to treat left ventricular (LV) thrombus after myocardial infarction (MI). Data on the use of direct oral anticoagulants (DOACs) in this setting are limited. The aim of the study was to assess the efficacy of apixaban vs. warfarin in treating LV thrombus after MI.The purpose of this study was to quantify the effect of anticoagulation therapy on LVT evolution using sequential imaging and to determine the impact of LVT regression on the incidence of thromboembolism, bleeding, and mortality.
Direct oral anticoagulants are frequently used to treat post-myocardial infarction (MI) left ventricular thrombus (LVT). This study was conducted to evaluate the efficacy and safety of use of apixaban, compared to the standard warfarin therapy, in post-MI LVT.Left ventricular (LV) thrombus is a feared complication of LV dysfunction associated with high rates of systemic embolism, morbidity, and mortality. Traditionally, LV thrombus has been associated with acute myocardial infarction (MI). The study is a prospective, randomized, multi-center open label trial comparing apixaban (at a dose of 5 mg twice daily) with s.c enoxaparin 1mg/kg BID followed by dose-adjusted warfarin to achieve a target international normalized ratio (INR) of 2.0 to 3.0 for 3 months in patients with LV thrombus detected by echocardiography 3 to 14 days .
DOACs are likely to be at least as effective and safe as VKA for stroke prevention and thrombus resolution in patients with LVT based on our review. If not, the efficacy of different DOACs for LVT management, the optimal duration, and comparative effectiveness is unknown. Our results suggest that apixaban is non-inferior to warfarin for treatment of patients with LV thrombus after acute MI with a 20% non-inferiority margin. Apixaban versus warfarin in patients with left ventricular thrombus: a pilot prospective randomized outcome blinded study investigating size reduction or resolution of left ventricular thrombus. J Clin Prev Cardiol 2020;9:150–4.
Results: Of the 514 patients with LV thrombi, 300 received warfarin, while 185 received DOAC therapy. DOAC use was most commonly apixaban (141/185, 76.2%) or rivaroxaban (46/185, 24.9%). Median follow-up was 351 days (interquartile range, [IQR], 51 .Keywords: Apixaban, direct oral anticoagulants, DOACs, left ventricular thrombus, Rivaroxaban, thrombolysis. 1. BACKGROUND. Left ventricular thrombus (LVT) is a common complication following acute myocardial infarction (AMI) with potential for significant morbidity and mortality.
Current guidelines recommend anticoagulation with a vitamin K antagonist to treat left ventricular (LV) thrombus after myocardial infarction (MI). Data on the use of direct oral anticoagulants (DOACs) in this setting are limited. The aim of the study was to assess the efficacy of apixaban vs. warfarin in treating LV thrombus after MI.
The purpose of this study was to quantify the effect of anticoagulation therapy on LVT evolution using sequential imaging and to determine the impact of LVT regression on the incidence of thromboembolism, bleeding, and mortality.Direct oral anticoagulants are frequently used to treat post-myocardial infarction (MI) left ventricular thrombus (LVT). This study was conducted to evaluate the efficacy and safety of use of apixaban, compared to the standard warfarin therapy, in post-MI LVT.Left ventricular (LV) thrombus is a feared complication of LV dysfunction associated with high rates of systemic embolism, morbidity, and mortality. Traditionally, LV thrombus has been associated with acute myocardial infarction (MI).
guidelines for Lv thrombus anticoagulation
The study is a prospective, randomized, multi-center open label trial comparing apixaban (at a dose of 5 mg twice daily) with s.c enoxaparin 1mg/kg BID followed by dose-adjusted warfarin to achieve a target international normalized ratio (INR) of 2.0 to 3.0 for 3 months in patients with LV thrombus detected by echocardiography 3 to 14 days .
apixaban for mural thrombus
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apixaban for lv thrombus|Lv thrombus treatment guidelines
